Table 1.
Overview of pulmonary pathology findings (n = 129).
| Pathological characteristic | Number of cases (%) |
|---|---|
| Epithelial | 110 (85%) |
| Diffuse alveolar damage and/or hyaline membranes | 97 (75%) |
| Desquamation and/or reactive hyperplasia of pneumocytes | 93 (72%) |
| Squamous metaplasia of alveolar epithelium | 25 (19%) |
| Multinucleated giant cells | 26 (20%) |
| Viral cytopathic changes, particles and/or inclusion bodies | 26 (20%) |
| Intra-alveolar fibrous plugs | 2 (2%) |
| Vascular | 76 (59%) |
| Capillary congestion | 58 (45%) |
| (Micro)thrombi | 50 (39%) |
| Alveolar hemorrhage | 42 (33%) |
| Alveolar proteinosis | 31 (24%) |
| Intra-alveolar fibrinous exudates and/or fibrin deposition (features of acute fibrinous and organizing pneumonia) | 34 (26%) |
| Capillary changes (i.e., proliferation or thickening, fibrin deposition, and endothelial cell detachment or - cell death) | 32 (25%) |
| Peri- or intravascular inflammatory infiltrate | 12 (9%) |
| Fibrotic | 28 (22%) |
| Interstitial fibrous changes (i.e., fibroblast hyperplasia, fibrosis, septal collagen deposition) | 43 (33%) |
| Microcystic honeycombing | 9 (7%) |
| Other | |
| Interstitial and/or intra-alveolar inflammatory infiltrate | 82 (64%) |
| Interstitial and intra-alveolar edema | 59 (46%) |