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. 2019 Nov 27;69(7):1248–1257. doi: 10.1136/gutjnl-2019-318532

Figure 1.

Figure 1

Identification and characterisation of m3. (A) Metagenome sequencing identified m3, as well as Fusobacterium nucleatum (Fn) and Clostridium hathewayi (Ch), to be significantly increased in faecal samples of patients with adenoma. (B) DNA sequence of m3 showed high similarity to Lachnoclostridium sp. YL32. (C) m3 encodes a putative reverse transcriptase (RTase) that maps to a group II intron RTase, lacking the first 60 amino acids but retaining the RTase conserved domain. A, adenoma; CRC, colorectal cancer; N, normal control.