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. 2019 Nov 27;69(7):1248–1257. doi: 10.1136/gutjnl-2019-318532

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Comparison and combination of bacterial markers with faecal immunochemical test (FIT). (A) Comparison of sensitivity and specificity of FIT, m3, combination of four makers (Fn, m3, Ch and Bc; LR4) and combination of bacterial markers with FIT in a subgroup of Hong Kong samples. LR4 combined with FIT performed best for colorectal cancer (CRC) detection, while m3 combined with FIT performed best for detecting adenoma. (B) Comparison of the sensitivities of FIT, LR4 and their combination in detecting CRC according to tumour-node-metastasis (TNM) stage subsets. (C) Comparison of the sensitivities of FIT, m3 and their combination in detecting non-advanced and advanced adenomas. All comparison of sensitivities was conducted by χ² tests. A, non-advanced adenoma; AA, advanced adenoma.