TABLE 1.
Based on the alignment of different viruses belonging to the Mononegavirales order, the residue content of the methyltransferase (MTase) and C-terminal domains (CTD) of their L protein was analyzed. For each virus, the MTase, CTD, and MTase+CTD total number of residues was determined. The isoelectric points (pI) were estimated with ProtParam. The difference between the MTase and CTD pIs were calculated and modeled with a blue gauge normalized to the greatest difference.