FIG 9.

Five HDACi-responsive host gene biomarkers do not predict in vivo HIV ca-RNA induction responses. Significant ca-RNA expression (A) versus no significant ca-RNA expression (B). Colored lines represent temporal gene expression data from individual participants. Each point is the average of three cDNA replicates, and error bars represent the standard error of the mean. Participant IDs (V) correspond to those in (20), and “significant ca-RNA induction” indicates statistically significant HIV RNA induction as defined in Archin et al. (20). VV represents a participant from a recently completed vorinostat/vaccine study.