TABLE 3.
Frequency of the Gag V280X variant with or without K286R in HLA-B*52:01-positive and -negative C-clade-infected individuals
| Gag type | B*52:01 Gag275–286 sequencea | Frequency (%) by HLA-B*52:01 status |
P value | |
|---|---|---|---|---|
| Positive (n = 31) | Negative (n = 107) | |||
| Wild type | RMYSPV SILDIK | 22.6 | 63.6 | 0.0001 |
| V280T | -----T------ | 16.1 | 18.7 | 1 |
| V280S | -----S------ | 19.4 | 0 | 0.0001 |
| V280A | -----A------ | 12.9 | 4.7 | 0.1144 |
| K286R | -----------R | 9.7 | 7.5 | 0.7102 |
| V280T/K286R | -----T-----R | 19.4 | 3.7 | 0.0088 |
| V280S/K286R | -----S-----R | 0 | 0.9 | 1 |
| V280A/K286R | -----A-----R | 0 | 0.9 | 1 |
a
The RI8 sequence is highlighted in the wild-type consensus sequence, and positions 280 and 286, respectively, are shown in boldface.