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Mutations within the RBS of H5N1 viruses generally reduce thermal stability. Residual hemagglutination titers were measured after 30-min incubations at a range of temperatures. Residual hemagglutination titers of RBS mutant viruses. The first column represents the titer before incubations, and subsequent columns show residual hemagglutination units (HAU) after incubation at the indicated temperature. Representative values from two independent experiments are presented.
