Table 3.

Step 3 – Different intervention strategies and their assessment.

Step 3 Decide on a general intervention strategy
Intervention type	Assessment
Restriction intervention	Supported by scientific evidence May have low level of acceptance Flexible, but demanding Can be adjusted to barriers
Enablement intervention	Supported by scientific evidence Higher degree of acceptance Flexible, but demanding and sustained programs may be challenging Can be adjusted to barriers
Education and guidelines	Not supported by evidence as sole measure, Complementary to restriction or intervention Can be adjusted to barriers
Antibiotic cycling	Not supported by scientific evidence Not very flexible Not very demanding
Behavourial change interventions	Promising Not enough studied in the context of antimicrobial stewardship
Mixed strategy	Appealing due to flexibility Better adjusted to actual barrier analysis Less generalizability