Table 5.

ROC curve parameters for PD‐1 and BTMs

	AUC	Standard Error	95% CI	P‐Value	Youden Index	Sensitivity (%)	Specificity (%)	Cutoff
CROSSL	0.66	0.07	0.52‐0.80	.037	0.38	62.86	75.00	0.78
PINP	0.76	0.06	0.63‐0.88	.001	0.44	86.11	58.33	44.93
OSTEOC	0.67	0.07	0.53‐0.81	.029	0.42	66.67	75.00	16.49
PD‐1	0.65	0.06	0.53‐0.76	.016	0.26	44.64	81.08	9.84

Abbreviations: AUC, area under the ROC curve; BTMs, bone turnover markers; CI, confidence interval; CROSSL, β‐crosslaps; OSTEOC, osteocalcin; PD‐1, programmed cell death protein 1; PINP, procollagen type 1 N‐terminal propeptide.