Table 4.
Multivariable Regressions of Creatinine-adjusted Urinary Log-transformed Glyphosate as Predictor of Log-transformed KIM-1, NGAL, ACR Biomarkers1
| All ages N=108 § | |||
|---|---|---|---|
| Increment per one log unit increase | KIM-1 | NGAL | ACR |
| Glyphosate Univariate | 0.974 (−17.92, 27.78) | −663.8 (–2462, 2641) | −0.287 (−6.773, 10.91) |
| Glyphosate Multivariable | −1.55 (−14.93, 17.62) | −887.8 (−1800, 662.2) | −5.05 (−14.14, 9.85) |
| Creatinine-adjusted models ¶ | |||
| Glyphosate Univariate | −1.648 (−15.22, 17.47) | −640.5 (–3242, 4079) | 7.603 (−9.522, 32.88) |
| Glyphosate Multivariable | −3.70 (−13.47, 10.26) | −819.8 (−1688, 657.8) | 0.858 (−13.80, 22.43) |
| Non-neonates N=98 §§ | |||
| Increment per one log unit increase | KIM-1 | NGAL | ACR |
| Glyphosate Univariate | −5.351 (−24.13, 27.39) | 1489 (–4383, 17944) | 3.002 (−10.66, 35.99) |
| Glyphosate Multivariable | −3.568 (−14.90, 15.96) | 395.3 (–5128, 12782) | 12.05 (−37.98, 106.6) |
| Creatinine-adjusted models ¶¶ | |||
| Glyphosate Univariate | −4.89 (−20.66, 22.43) | 2083 (–5679, 23234) | 8.24 (−16.60, 54.17) |
| Glyphosate Multivariable | −3.73 (−14.45, 14.88) | 132.8 (–5165, 11668) | 10.37 (−25.33, 72.33) |
§
KIM-1 N=99; NGAL N=95; ACR N=96. Multivariable regression models controlling for demographic covariates age, sex, and maternal education, where maternal education missing observations were imputed as the majority category “Equal or Greater Than High School”.
¶
Creatinine-adjusted regression models KIM-1 N=95; NGAL N=92; ACR N=96.
§§
KIM-1 N=89; NGAL N=86; ACR N=86. Multivariable regression models controlling for demographic covariates age, sex, and maternal education, where maternal education missing observations were imputed