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. Author manuscript; available in PMC: 2021 Jul 15.
Published in final edited form as: Behav Brain Res. 2020 May 8;390:112659. doi: 10.1016/j.bbr.2020.112659

Figure 3.

Figure 3.

Adolescent- and adult-onset METH self-administration in rats of both sexes. (A) Daily METH intake (mg/kg) across 7 days of short access (ShA) and 14 days of long access (LgA) self-administration. ^ p < 0.05 vs. all other ShA sessions. Session intake vs. first LgA session: * p < 0.05 for females, # p < 0.01 for males, @ p < 0.05 for adolescent-onset rats, $ p < 0.05 for adult-onset rats. (B) Daily METH intake (mg/kg) during the first hour of each self-administration session. @ p < 0.05 vs. first LgA session for adolescent-onset rats. (C) METH intake (mg/kg) on the first and last LgA session. @ p < 0.05 age within session, ^ p < 0.05 vs. first LgA session. (D) Cumulative METH intake (mg/kg) across all self-administration sessions. Each dot represents one individual rat. @ p < 0.05 age effect.