Adolescent- and adult-onset saccharin self-administration in rats of both sexes. (A) Daily saccharin intake (ml/kg) across 7 days of short access (ShA) and 14 days of long access (LgA) self-administration. * p < 0.05 vs. males, @
p < 0.05 adolescent-onset vs. adult-onset. (B) Daily saccharin intake (ml/kg) during the first hour of each self-administration session. * p < 0.05 for females vs. all other LgA sessions, Session intake vs. first LgA session: #
p < 0.01 for males, @
p < 0.05 for adolescent-onset rats, $
p < 0.05 for adult-onset rats. (C) Saccharin intake (ml/kg) on the first and last LgA session. * p < 0.05 vs. males, @
p < 0.05 vs. adolescent-onset. (D) Cumulative saccharin intake (L/kg) across all self-administration sessions. Each dot represents one individual rat. * p < 0.05 vs. males, @
p < 0.05 age effect.