TABLE 4.
HOMA-IR | Model 1 | Model 2 | Model 3 |
---|---|---|---|
Baseline | 2.30 (1.93, 2.75) | 5.44 (4.30, 6.88) | 1.85 (1.57, 2.13) |
1 y | 5.54 (4.19, 7.35) | 6.90 (5.10, 9.35) | 1.76 (1.45, 2.08) |
3 y | 3.97 (2.79, 5.63) | 6.25 (4.16, 9.39) | 2.38 (1.80, 2.96) |
1-y change | 1.55 (1.28, 1.87) | 2.99 (2.38, 3.76) | 1.29 (1.02, 1.56) |
Values are ORs (95% CIs). Model 1: sex, age, BMI, waist circumference, physical activity, and smoking, with further inclusion of baseline HOMA-IR for 1 and 3 y and for 1-y changes. Model 2: model 1 + multimetabolite score. Model 3: multimetabolite score.