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. 2019 Feb 23;109(3):626–634. doi: 10.1093/ajcn/nqy262

TABLE 5.

AUCs (95% CIs) for prediction models for high HOMA-IR (median or higher)1

HOMA-IR Model 1 Model 2 Model 3
Baseline 0.69 (0.66, 0.73) 0.81 (0.79, 0.84)* 0.81 (0.78, 0.84)*
1 y 0.84 (0.80, 0.88) 0.83 (0.82, 0.85) 0.75 (0.71, 0.78)*,#
3 y 0.81 (0.75, 0.86) 0.81 (0.76, 0.85) 0.72 (0.70, 0.74)*,#
1-y change 0.57 (0.53, 0.62) 0.69 (0.66, 0.72)* 0.66 (0.62, 0.69)*,#
1

Model 1: sex, age, BMI, waist circumference, physical activity, and smoking, with further inclusion of baseline HOMA-IR for 1 and 3 y and for 1-y changes. Model 2: model 1 + multimetabolite score. Model 3: multimetabolite score. *,#P < 0.05: *model 2 compared with model 1 or model 3 compared with model 1; #model 3 compared with model 2.