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. 2020 Jan 27;24(3):276–279. doi: 10.4103/jisp.jisp_459_19

Table 1.

Describes the differential diagnosis of the present case

Lesion Clinical features Histo-pathological features Differentiating features
Angiosarcoma Mimics aggressive pyogenic granuloma Made of disorganized proliferation of endothelial cells
Interconnecting vascular channels
Occurs in older age group
Endothelial cells are atypical and polyhedral
Vascular channels invade the deeper connective tissue
Capillary hemangioma Multinodular bluish red in color Proliferation of capillaries More common in children
Endothelial cells are more plump
No acute inflammatory cells
Epitheloid hemangioendothelioma Exophytic, ulcerated, painless red mass Proliferation of epitheloid like endothelial cells Rare in the oral cavity
More common in submandibular region
Intracytoplasmic vacuoles in epitheloid cells
Kaposi Sarcoma Raised nodule with bright red appearance Atypical vascular channels, extravasated RBCs, inflammatory cells HIV associated lesion
Occurs in the palate
Vascular clefts, intracellular hyaline globules
Bacillary Angiomatosis Raised, nodular lesion appearing bright red.
Occasional alveolar bone loss
Proliferating capillaries arranged around ectatic vessels HIV associated lesion
Epitheloid endothelial cells noted
Eosinophilic aggregates containing fibrin and bacilli