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. 2020 Jun 4;57(2):500–508. doi: 10.3892/ijo.2020.5077

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Copyright: © Yu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effects of MH, EDA and Bru on spatial learning, memory and mitochondrial function in rats subjected to MCAO. (A and B) The escape latency and quadrant occupancy of the rats were evaluated by Barnes maze task on day 12 after MCAO; n=10 mice per group. (C and D) Representative confocal microscopy images and statistical analysis of MitoRed fluorescence staining. Scale bar: 20 µm. Magnification, x400. ^***P<0.001 vs. sham. ^###P<0.001 vs. MCAO. ^{^^^}P<0.001 vs. MCAO + MH + EDA. MCAO, middle cerebral artery occlusion; MH, mild hypothermia; EDA, edaravone; Bru, brusatol.