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FAM83A knockdown activates integrins α1, α3, α5, β4 and β5 in mouse xenograft models. (A-F) Immunofluorescence analysis of integrin α1, α3, α5, β4 and β5 protein expression (green) in HeLa xenograft tumors generated using cells transfected with nc-shRNA or FAM83A-sh. Nuclear DNA was stained with DAPI (blue). **P<0.01 vs. HeLa/nc-shRNA. sh/shRNA, short hairpin RNA; FAM83A, family with sequence similarity 83 member A; nc, negative control.
