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. 2020 Jun 2;57(2):466–477. doi: 10.3892/ijo.2020.5076

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Overexpression of lncRNA CASC7 suppressed non-small cell lung cancer cell invasion and migration in vitro (A and B) The effect of CASC7 overexpression on the invasion of A549 and H358 cells was determined by Transwell assay with Matrigel coating (magnification, ×200). (C and F) The effect of CASC7 overexpression on the expression of epithelial-to-mesenchymal transition-related genes, including E-cadherin, N-cadherin, fibronectin and vimentin, was assessed by western blotting. (D and E) The effect of CASC7 overexpression on the migration of A549 and H358 cells was determined by wound healing assay (magnification, ×200). Data are presented as means ± standard deviation from three independent experiments; ^**P<0.01 vs. pcDNA-vector.