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Schematic diagram of the signaling pathway through which CASC7 inhibits the proliferation, invasion and migration of NSCLC cells. Overexpression of CASC7 effectively inhibits growth and invasion of NSCLC cells through upregulating the expression of the PTEN tumor suppressor gene via sequestration of miR-92a. NSCLC, non-small cell lung cancer; PTEN, phosphatase and tensin homolog.
