Table I.
Groups | Tgel (°C)c | Storage modulus (Pa)d |
---|---|---|
Free gela | 21.6±1.2 | 812 |
Gel+CDb | 19±2.0 | 881 |
Gel+CUR | 17.6±1.2 | 1,206 |
Gel+DOX | 21±2.0 | 1,009 |
Gel+CD-CUR | 19.6±1.2 | 1,077 |
Gel+DOX+CD-CUR | 18.3±1.2 | 1,392 |
The concentration of PLGA-PEG-PLGA hydrogel was 20% wt;
The dose of each trapped drug in hydrogel was 1 mg/ml;
Sol-gel transition temperature evaluated by the vial inversion method;
Evaluated by the rheometer. CD-CUR, β-cyclodextrin curcumin; DOX, doxorubicin.