Table 4:
Imaging and Autopsy correlation of right ventricular strain ECG pattern
| Development Cohort | Validation Cohort | Entire Cohort | ||||
|---|---|---|---|---|---|---|
| RV Strain by ECG (n = 35) | No RV Strain by ECG (n = 38) | RV Strain by ECG (n = 21) | No RV Strain by ECG (n = 19) | RV Strain by ECG (n = 56) | No RV Strain by ECG (n = 57) | |
| Chest CT Angiogram for Pulmonary Embolism*, n | 5 | 2 | 5 | 1 | 10 | 3 |
| Positive, n (%) | 0 | 0 | 2 (40) | 0 | 2 (20) | 0 |
| Negative, n (%) | 5 (100) | 2 (100) | 3 (60) | 1 (100) | 8 (80) | 3 (100) |
| Autopsy - Pulmonary embolism†, n | 7 | 5 | 6 | 5 | 13 | 10 |
| Positive, n (%) | 2 (29) | 0 | 2 (33) | 0 | 4 (31) | 0 |
| Negative, n (%) | 5 (71) | 5 (100) | 4 (67) | 5 (100) | 9 (69) | 10 (100) |
| Echocardiogram - post arrest‡, n | 14 | 7 | 8 | 7 | 22 | 14 |
| New isolated RV dysfunction§, n(%) | 5 (36) | 0 | 4 (50) | 1 (14)‖ | 9 (41) | 1 (7) |
| New isolated LV dysfunction, n(%) | 0 | 1 (14) | 0 | 2 (29) | 0 | 3 (21) |
| New biventricular dysfunction, n(%) | 2 (14) | 2 (29) | 1 (13) | 0 | 3 (14) | 2 (14) |
| No change, n(%) | 7 (50) | 4 (57) | 3 (37) | 4 (57) | 10 (45) | 8 (57) |
Positive result denote studies showing evidence of massive or submassive pulmonary embolus. Negative results denote studies showing no pulmonary embolism, segmental or subsegmental embolus without evidence of right ventricular strain by CT. Positive studies include those performed up to 24 hours pre-arrest, and those post-arrest. Negative studies must be performed post-arrest
Positive autopsy shows large burden of pulmonary embolism deemed to be the likely cause of cardiac arrest
Performed within 24 hours post-cardiac arrest
Enlargement, decrease in systolic function, or volume and/or pressure overload not previously present
his patient developed possible R strain C pattern post-arrest
Abbreviations. CT: computed tomography, LV: left ventricle, RV: right ventricle