Table 3.

10-months echocardiography

	Before	After	Delta (%)	P
Weight, kg	120±15	83±12	-34 (-29%)	<0.001
BMI, kg/sqm	44±5	31±5	-12 (-29%)	<0.001
Epicardial fat, mm	4.7±1	3.5±0.7	-1.2 (-24%)	<0.001
Left ventricle
End-diastolic diameter, mm	48±3	47±3	-1 (-2%)	0.133
End-diastolic volume, ml	117±24	101±20	-16 (-12%)	0.001
End-systolic volume, ml	44±10	37±9	-8 (-16%)	<0.001
Septal thickness, mm	10±1	9±1	-1 (-9%)	0.004
Posterior wall thickness, mm	10±1	9±1	-1 (-8%)	0.007
Mass, g	197±41	163±30	-34 (-17%)	0.031
Left atrium
AP diameter, mm	40±4	37±3	-2 (-5%)	0.010
SI diameter, mm	57±4	54±5	-2 (-3%)	0.218
area, cm²	22±3	19±2	-2 (-9%)	0.002
Volume, ml	64±17	57±14	-8 (-10%)	0.016
Right ventricle
Diastolic diameter, mm	37±3	36±3	-1 (-3%)	0.029
TAPSE, mm	23±4	24±5	+1 (5%)	0.512
PAPs, mmHg	28±4	27±4	+1 (+2%)	0.516
Right atrium
Area, cm²	18±3	16±2	+2 (+10%)	0.009
Volume, ml	51±12	43±10	-9 (-16%)	0.002
Aorta
Aortic root, mm	31±3	32±3	+0 (0%)	0.272
Ascending aorta, mm	30±3	31±3	+1 (+3%)	0.338
Systolic function
EF, %	61±3	64±3	+2 (+4%)	0.002
Lateral S2, cm/s	9.8±1.2	10.4±1.5	+1 (+7%)	0.020
GLS, %	-17±2	-20±1	-3 (-19%)	<0.001
Diastolic function
E, cm/s	82±14	83±15	+0 (0%)	0.738
A, cm/s	67±14	66±16	-1 (-2%)	0.764
E/A	1.28±0.34	1.35±0.43	+0.06 (+5%)	0.412
DT, ms	173±31	183±24	+10 (+6%)	0.156
Lateral e’, cm/s	13.49±3.65	14.59±3.25	+1.11 (+10%)	0.029
Lateral E/e’	6.31±1.17	5.82±1.06	-0.49 (-7%)	0.012
Septal e’, cm/s	9.05±1.95	10.19±2.01	+1.13 (+15%)	0.022
Septal E/e’	9.24±1.68	8.32±1.80	-0.96 (-9%)	0.023
Valves
Aortic insufficiency	0 (0%)	5 (13%)
Mitral insufficiency	16 (39%)	14 (35%)
Tricuspid insufficiency	10 (26%)	10 (26%)
Pulmonary insufficiency	0 (0%)	0 (0%)
NT-proBNP, pg/ml	29±29	52±32	+23 (+296%)	0.002

BMI, body mass index; AP, antero-posterior; SI, superior-inferior; TAPSE, tricuspid annular plane systolic exertion; PAPs, systolic pulmonary artery pressure; EF, ejection fraction; GLS, global longitudinal strain; DT, deceleration time, NT-proBNP, N-terminal prohormone of brain natriuretic peptide.