Figure 4.

Performance during the spatial probe trial of the separate 3-d Morris water maze test administered just before killing, at 12 months postinjection. The mean relative distance swum (A), the average number of annulus crossings (B), and the actual swim paths taken by representative animals from the different groups (C) are illustrated. Consistent with the observations at the three-month time point, no long-term impairments in reference memory abilities were produced by the α-syn treatment.