Table 1.

Electrophysiological properties of ACC and lOFC deep-layer pyramidal neurons from water-drinking and ethanol-drinking mice

Drinking length	Condition	RMP(mV)	AP threshold(mV)	AP amplitude(mV)	AP width(ms)	AP rise(ms)	AHP amplitude(mV)
ACC
1 d	Water	–69.73 ± 2.18	–42.19 ± 0.90	62.25 ± 3.1	2.38 ± 0.14	0.40 ± 0.01	13.15 ± 0.77
	EtOH	–66.39 ± 1.82	–42.06 ± 0.94	70.41 ± 4.5	2.23 ± 0.10	0.43 ± 0.02	14.25 ± 0.81
1 week	Water	–69.99 ± 2.03	–41.15 ± 1.16	63.02 ± 1.8	2.20 ± 0.10	0.39 ± 0.02	15.14 ± 0.77
	EtOH	–66.46 ± 1.96	–39.50 ± 1.39	63.29 ± 2.1	1.97 ± 0.06	0.38 ± 0.01	13.79 ± 1.08
4 weeks	Water	–70.89 ± 1.81	–44.74 ± 1.43	60.80 ± 2.4	1.71 ± 0.16	0.35 ± 0.01	13.62 ± 1.03
	EtOH	–69.04 ± 2.36	–44.19 ± 1.15	57.80 ± 2.7	1.94 ± 0.13	0.38 ± 0.02	13.07 ± 0.87
7 weeks	Water	–68.70 ± 1.31	–45.68 ± 1.86	60.12 ± 2.9	2.07 ± 0.09	0.39 ± 0.02	12.29 ± 1.18
	EtOH	–70.88 ± 2.10	–44.74 ± 1.14	59.01 ± 1.9	2.33 ± 0.17	0.42 ± 0.03	13.12 ± 1.04
lOFC
1 d	Water	–68.98 ± 0.8	–38.32 ± 1.41	63.48 ± 2.07	1.82 ± 0.07	0.37 ± 0.01	16.14 ± 0.63
	EtOH	–69.47 ± 0.57	–41.89 ± 1.19	63.89 ± 1.94	1.81 ± 0.08	0.38 ± 0.01	15.19 ± 0.42
1 week	Water	–69.71 ± 0.67	–37.76 ± 1.32	64.40 ± 2.11	1.76 ± 0.04	0.36 ± 0.01	15.92 ± 0.56
	EtOH	–68.44 ± 0.64	–37.99 ± 1.49	61.49 ± 1.96	1.92 ± 0.07	0.38 ± 0.01	15.73 ± 0.67
4 weeks	Water	–69.97 ± 0.68	–37.50 ± 1.61	63.25 ± 2.15	1.98 ± 0.10	0.39 ± 0.01	16.04 ± 0.59
	EtOH	–67.87 ± 0.41*	–43.80 ± 1.38*	65.25 ± 2.13	1.73 ± 0.08	0.37 ± 0.01	13.99 ± 0.69*
7 weeks	Water	–70.07 ± 0.54	–40.29 ± 1.20	60.43 ± 2.07	1.71 ± 0.06	0.37 ± 0.01	15.17 ± 0.43
	EtOH	–69.10 ± 0.47	–41.18 ± 1.47	65.16 ± 2.29	1.81 ± 0.05	0.37 ± 0.01	15.01 ± 0.67

Values are mean ± SEM. Two-tailed unpaired t test was used to compare differences in electrophysiological properties between water control and ethanol drinking mice. Asterisk in bold font = p < 0.05 vs water drinking controls.