Table 3.

Association of hsCRP (quartiles) with all-cause mortality over a mean follow-up of 8.0±1.1 years

			hsCRP (mg/L)
Models	Total N=14 238 (100%)	Deaths n=444 (3.12%)	Quartile 1 HR (reference)	Quartile 2 HR (95% CI)	Quartile 3 HR (95% CI)	Quartile 4 HR (95% CI)
Model 1*			1.0	1.43 (1.05 to 1.96)	1.65 (1.22 to 2.23)	2.23 (1.67 to 2.98)
Model 2†			1.0	1.45 (1.06 to 1.99)	1.74 (1.28 to 2.35)	2.47 (1.84 to 3.30)
Model 3‡			1.0	1.47 (1.07 to 2.02)	1.75 (1.29 to 2.39)	2.43 (1.80 to 3.30)
Model 4§			1.0	1.45 (1.05 to 2.01)	1.61 (1.17 to 2.22)	2.08 (1.52 to 2.85)
Model 5¶			1.0	1.45 (1.05 to 2.01)	1.54 (1.11 to 2.13)	1.95 (1.42 to 2.69)

*Model 1: adjusted for age.

†Model 2: model 1 and sex.

‡Model 3: model 2 and ethnicity and body mass index.

§Model 4: model 3 and level of education, alcohol consumption, smoking status, physical activity level, and fruits and vegetables consumption.

¶Model 5: model 4 and systolic blood pressure, use of antihypertensive drugs, diabetes mellitus, depression, chronic obstructive pulmonary disease, cardiovascular disease and cancer.

hsCRP, high-sensitivity C reactive protein.