Table 5.
Multivariable Linear Regression Models of Relationship Between Lactation, Cardiometabolic Risk Factors, and Carotid Intima-Media Thickness Among Women with a History of Hypertensive Disorders of Pregnancy (Adjusted)
Model 1a |
Model 2b |
|||||
---|---|---|---|---|---|---|
LSMdiff | 95% CI | p | LSMdiff | 95% CI | p | |
Systolic BP (mmHg) | ||||||
Some lactationc | −6.65 | −13.7 to 0.47 | 0.070 | −3.69 | −10.8 to 3.44 | 0.313 |
Lactation ≥6 months | −4.17 | −12.3 to 4.05 | 0.322 | −1.55 | −9.58 to 6.48 | 0.706 |
Diastolic BP (mmHg) | ||||||
Some lactation | −8.31 | −13.9 to −2.68 | 0.005 | −5.83 | −10.9 to −0.75 | 0.026 |
Lactation ≥6 months | −4.73 | −12.0 to 2.62 | 0.210 | −2.54 | −9.49 to 4.42 | 0.476 |
Total cholesterol (mg/dL) | ||||||
Some lactation | 11.6 | −6.09 to 29.4 | 0.201 | 13.9 | −4.24 to 32.2 | 0.136 |
Lactation ≥6 months | 7.15 | −16.7 to 31.0 | 0.559 | 9.19 | −15.7 to 34.1 | 0.472 |
LDL (mg/dL) | ||||||
Some lactation | 10.8 | −2.78 to 24.5 | 0.122 | 12.7 | −1.60 to 27.1 | 0.085 |
Lactation ≥6 months | 6.76 | −11.8 to 25.3 | 0.477 | 8.46 | −11.0 to 27.9 | 0.398 |
HDL (mg/dL) | ||||||
Some lactation | −2.24 | −8.85 to 4.37 | 0.508 | −4.73 | −11.0 to 1.54 | 0.142 |
Lactation ≥6 months | −1.85 | −9.55 to 5.86 | 0.640 | −4.05 | −11.0 to 3.54 | 0.298 |
Triglycerides (mg/dL) | ||||||
Some lactation | 15.3 | −18.1 to 48.7 | 0.372 | 28.7 | −10.5 to 67.9 | 0.155 |
Lactation ≥6 months | 9.60 | −27.6 to 46.8 | 0.614 | 21.4 | −24.2 to 67.2 | 0.360 |
Glucose (mg/dL) | ||||||
Some lactation | −9.61 | −26.2 to 7.00 | 0.259 | −8.64 | −25.0 to 8.56 | 0.327 |
Lactation ≥6 months | −8.67 | −25.2 to 7.89 | 0.307 | −7.80 | −24.9 to 9.30 | 0.373 |
CCA IMT (mm) | ||||||
Some lactation | 0.07 | 0.02–0.11 | 0.004 | 0.07 | 0.03–0.12 | 0.003 |
Lactation ≥6 months | 0.06 | −0.00 to 0.12 | 0.053 | 0.07 | 0.01–0.13 | 0.036 |
ICA IMT (mm) | ||||||
Some lactation | 0.03 | −0.03 to 0.10 | 0.306 | 0.04 | −0.02 to 0.11 | 0.198 |
Lactation ≥6 months | −0.03 | −0.11 to 0.06 | 0.507 | −0.02 | −0.10 to 0.07 | 0.676 |
Bulb IMT (mm) | ||||||
Some lactation | 0.09 | −0.00 to 0.18 | 0.062 | 0.10 | 0.00–0.20 | 0.043 |
Lactation ≥6 months | 0.07 | −0.06 to 0.21 | 0.329 | 0.09 | −0.06 to 0.23 | 0.262 |
Mean IMT (mm) | ||||||
Some lactation | 0.07 | 0.025–0.11 | 0.002 | 0.08 | 0.03–0.12 | 0.001 |
Lactation ≥6 months | 0.04 | −0.02 to 0.11 | 0.209 | 0.05 | −0.01 to 0.12 | 0.137 |
AD (mm) | ||||||
Some lactation | −0.01 | −0.24 to 0.23 | 0.937 | 0.06 | −0.19 to 0.31 | 0.634 |
Lactation ≥6 months | −0.10 | −0.40 to 0.21 | 0.528 | −0.03 | −0.34 to 0.28 | 0.842 |
Adjusted for age, race, income, education, smoking, time from last pregnancy, and total lifetime parity.
Adjusted for Model 1+BMI.
Never lactated is the reference group.