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. 2020 Jun 22;18(6):e3000722. doi: 10.1371/journal.pbio.3000722

Fig 1. HS conditions induce rapid Na+ influx in MΦs.

Fig 1

(A) Total Na+ content of RAW264.7 MΦs ± 10 ng/ml LPS under NS or HS (NS + 40 mM NaCl) conditions (mean ± SD; n = 11–12; Student t test ± Welch correction; *p < 0.05). (B) Relative [Na+]i of RAW264.7 MΦs. Traces of RAW264.7 MΦs stimulated with HS, LPS, or both at t = 10 s (mean ± SD; n = 7–9). (C) Relative [Na+]i of RAW264.7 MΦs. Traces of RAW264.7 MΦs stimulated with HS or 80 mM urea at t = 10 s (mean ± SD; n = 5). For numerical raw data, please see S1 Data. HS, high salt; LPS, lipopolysaccharide; MΦ, monocyte/macrophage-like cell; [Na+]i, intracellular Na+ in situ; NS, normal salt.