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. 2020 May 26;16(5):e1007932. doi: 10.1371/journal.pcbi.1007932

Table 2. Constants, parameters, and default steady state values for variables.

Symbol Value Description
Constants
F 96485.33 C mol-1 Faraday constant
R 8.31446 J K-1 mol-1 Universal gas constant
T 310.15 K Absolute temperature (= 37˚C)
Parameters
τriseAMPA 0.2 ms AMPA rise time constant [59]
τdecayAMPA 1.7 ms AMPA decay time constant [59]
τriseNMDA 2.04 ms NMDA rise time constant [62]
τdecayNMDA 75.2 ms NMDA decay time constant [62]
αGABA 5 mM-1 ms-1 GABAA receptor binding rate [63]
βGABA 0.18 ms-1 GABAA receptor unbinding rate [63]
PKCC2 0.001 mM-1 s-1
1.9297 x 10−5 mA mM-2 cm-2
Pump strength for potassium-chloride cotransporter 2 (KCC2)
[K+]i 140 mM Internal potassium concentration
[Na+]i 10 mM Internal sodium concentration
[HCO3-]i 12 mM Internal bicarbonate concentration
[Cl-]o 135 mM External chloride concentration
[K+]o 4.0 mM External potassium concentration
[Na+]o 140 mM External sodium concentration
[HCO3-]o 23 mM External bicarbonate concentration
Variables (default steady state values)
ECl- -92.42 mV Reversal potential for chloride
[Cl-]i 4.25 mM Internal chloride concentration
EGABA -77.41 mV Reversal potential for GABAAR
Vm -71.35 mV Membrane Voltage