Table 2.

Symptoms and sign of Covid-19 infection and management in cardiomyopathies (CMP) and ion channel diseases (ICD). HFpEF: heart failure with preserved ejection fraction; HFrEF: heart failure with reduced ejection fraction

SYMPTOM	CLINICAL CONTEXT	MANAGEMENT
Fever	anamnesis: previous contact with Covid19+, onset, and progression, degree (>or < 37.5°), association with other symptoms	Hydratation (according to clinical status) and paracetamol ECG monitoring in Brugada Syndrome. Consider hospitalization in high risk patients (BS type 1 with no ICD; previous syncope; persistent fever, with no response to paracetamol)
Cough	anamnesis: previous contact with Covid19+, type of cough (productive or dry), previous or recent onset, association with other symptoms	Teleconsultation ProBNP or BNP (suspect of new onset heart failure), when possible Consider hospitalization in high risk patients (emergency; end stage cardiomyopathies; high suspect of HFREF/HFPEF)
Dyspnoea	anamnesis: previous contact with Covid19+, type and degree, previous or recent onset, association with other symptoms	Teleconsultation ProBNP or BNP (suspect of new onset heart failure), when possible Consider hospitalization in high risk patients (emergency; end stage cardiomyopathies; high suspect of HFREF/HFPEF)
Fatigue	anamnesis: previous contact with Covid19+, type (i.e. myalgia, cramps, etc) and degree, previous of recent onset, association with other symptoms	Teleconsultation When useful, suggest potassium/magnesium supplementation ProBNP or BNP (suspect of new onset heart failure), when possible Consider hospitalization in high risk patients (emergency; end stage cardiomyopathies; high suspect of HFREF/HFPEF)
Diarrhea	anamnesis: previous contact with Covid19+, association with other symptoms	Teleconsultation Hydratation (according to clinical status) Risk of hypokaliemia particularly dangerous in patients with prolonged QT (LQTs, drugs, HCM) Potassium/magnesium supplementation