Figure 3.

Overexpression of miR-144-3p suppresses cell invasion and migration. CAL-27 and SCC-4 cells were transfected with the 20 nM miR-144-3p mimics or mimics-NC for 48 h, and the cells were used for analysis. (A and B) The expression levels of E-cadherin and N-cadherin were measured by western blot analysis. (C and D) Cell invasion was determined by Transwell assay. (E and F) Cell migration was detected by wound healing assay. Data are presented as the means ± SD of 3 independent experiments. ^**P<0.01 vs. mimics NC.