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. 2020 May 20;46(2):782–794. doi: 10.3892/ijmm.2020.4611

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Copyright: © Tian et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Changes in protein expression levels following the administration of AOAA, U0126 or PF-04856264 in dorsal root ganglions of SNI rats. (A) Expression levels of CBS, MEK, p-MEK, ERK, p-ERK, Na_v1.7 and GAPDH in each group. Relative expression of (B) CBS, (C) p-MEK/MEK, p-ERK/ERK and (D) Na_v1.7 in each group. ^*P<0.05 vs. Sham group. ^#P<0.05 vs. SNI+Vehicle group. n=6 per group. AOAA, O-(carboxymethyl) hydroxylamine hemihydrochloride; SNI, spared nerve injury; MEK, mitogen-activated protein kinase kinase; ERK, extracellular signal-regulated kinase; p, phosphorylated; cystathionine β-synthetase; Nav1.7, voltage-gated sodium channel 1.7.