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. 2020 May 25;46(2):571–582. doi: 10.3892/ijmm.2020.4616

Figure 5.

Figure 5

LINC00473 influences the viability and radiosensitivity of esophageal squamous cell cancer cells by regulating miR-497-5p. Following pcDNA-NC, pcDNA-LINC00473 or pcDNA-LINC00473/miR-497-5p mimic transfection into KYSE-30 cells, and sh-NC, sh-LINC00473 or sh-LINC00473/miR-497-5p inhibitor transfection into TE-5 cells, cellular viability/proliferation was detected using the Cell Counting Kit-8 assay (A). Following X-ray irradiation (0, 2, 4, 6 and 8 Gy) for 2 weeks, the survival ratio of colony-forming cells was detected using a colony formation assay (B). *P<0.05, **P<0.01 and ***P<0.001, NC vs. LINC00473 and sh-NC vs. sh-LINC0473. #P<0.05, ##P<0.01 and ###P<0.001, LINC00473 vs. LINC00473 + miR-497-5p and sh-LINC00473 vs. sh-LINC00473 + miR-497-5p inhibitors. miR, microRNA; NC, negative control; sh, short hairpin (RNA).