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. 2020 Feb 24;21(4):1489–1498. doi: 10.1021/acs.biomac.0c00061

Figure 7.

Figure 7

PDT effect of empty TPC–CS NPs upon treatment with ferroptosis inhibitors in the breast cancer cell lines MDA-MB-231 (A) and MCF7 (B). The cells were incubated with TPC0.1–CS NPs for 24 h, followed by 1 h preincubation with liproxstatin-1 (Liproxst, 1 μM) or deferiprone (DFP, 100 μM) before a 2 min light treatment. Toxicity of the treated cells was measured by the MTT assay after 48 h incubation. The data are shown as percent of control for each cell line not treated with TPC–CS NPs. The graphs show mean values ± SEM from three independent experiments. *p < 0.05; **p < 0.01; ***p < 0.005 for comparison of cells treated with Liprox, and ##p < 0.01; ###p < 0.005 for comparison of cells treated with DFP.