Table 2.

Cognitive test scores by cystatin C tertile groups

Cognitive Test	Cystatin C < 1.35	Cystatin C 1.35–1.81	Cystatin C 1.82+	P-value†
	Mean + SD	Mean + SD	Mean + SD
Global Cognition
MMSE	27.8 + 1.9	27.0 + 3.3	26.7 + 3.4	0.12
3MS	94.7 + 4.5	91.7 + 9.4	90.9 + 11.3	0.04
Language
Boston Naming Test	13.1 + 2.2	13.0 + 1.9	13.5 + 1.6	0.42
Animal Fluency	15.6 + 4.4	15.3 + 5.4	14.5 + 5.0	0.46
Letter F Fluency	13.2 + 5.2	12.7 + 5.3	13.6 + 4.1	0.60
Recent Memory
CVLT Trial 1	5.1 + 1.9	5.0 + 2.0	4.8 + 1.8	0.69
CVLT Trial 4	7.7 + 1.2	7.3 + 1.7	7.3 + 1.6	0.26
CVLT Sum 1 to 4	26.9 + 4.9	25.8 + 6.6	25.6 + 5.7	0.44
CVLT Short Delay	7.2 + 1.7	6.8 + 2.2	6.5 + 2.5	0.24
CVLT Long Delay	6.2 + 2.3	6.0 + 2.9	5.7 + 3.1	0.54
CVLT Cued Long Delay	6.6 + 2.1	6.4 + 2.6	6.6 + 2.3	0.92
Executive Function
Trails A	55 + 24	72 + 34	65 + 34	0.01
Trails B	145 + 74	202 + 83	200 + 90	0.0002
Trails B - Trails A	91 + 62	130 + 67	135 + 78	0.002
Psychomotor Speed
Trails C	22 + 10	34 + 33	28 + 16	0.02
Visual-spatial
Clock	6.1 + 1.9	5.9 + 2.0	6.3 + 2.0	0.54
CERAD Constructions	9.8 + 1.1	9.1 + 1.3	9.6 + 1.0	0.007
Attention/Working Memory
Digit Span Forward	9.2 + 2.0	8.9 + 1.8	9.1 + 1.8	0.60
Digit Span Backward	5.9 + 2.3	5.6 + 2.1	5.5 + 1.8	0.54
Digit Span Total	15.2 + 3.8	14.5 + 3.4	14.6 + 3.0	0.57

^†for difference among cystatin C tertile groups