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. 2020 Jun 4;5(11):e138999. doi: 10.1172/jci.insight.138999

Figure 1. Detection of NETs in sera of COVID-19 patients.

Figure 1

Sera from COVID-19 patients (n = 50) and healthy controls (n = 30) were assessed for cell-free DNA (A), myeloperoxidase-DNA (MPO-DNA) complexes (B), or citrullinated histone H3 (Cit-H3) (C). COVID-19 samples were compared with controls by Mann-Whitney U test; ***P < 0.001, ****P < 0.0001. For the COVID-19 samples, correlation of cell-free DNA with MPO-DNA (D) and Cit-H3 (E) was assessed. Spearman’s correlation coefficients were calculated and are shown in the panels.