Skip to main content
. 2020 Jun 4;5(11):e137686. doi: 10.1172/jci.insight.137686

Figure 6. Distribution of hitABC transporter genes in streptococcal species and immunoreactivity of recombinant HitA.

Figure 6

(A) Distribution of the hitABC transporter genes and the adjacent irr-ihk two-component regulatory genes in other streptococcal species (Streptococcus dysgalactiae subspecies equisimilis [SDSE] strain GGS124, Streptococcus sanguinis strain SK36, Streptococcus cristatus strain NCTC12479, and Streptococcus gordonii strain NCTC7868). Percentages refer to amino acid identities compared with proteins made by serotype M1 GAS reference strain MGAS2221. (B) SDS-PAGE gel showing the purified recombinant GAS lipoproteins HitA and FhuD. BSA was added as a control. (C) Immunoreactivity of purified HitA and FhuD with pooled human immune globulin.