Table 1.
Characteristics of Patients with Complete Follow-Up According to Their Classification at Baseline
| Studied Concordant | Studied Discordant | Total | p¥ | |
|---|---|---|---|---|
| (n=145) | (n=73) | (n=218) | ||
| Male sex | 136 (93.8%) | 72 (98.6%) | 208 (95.4%) | 0.107 |
| Age | 70.48 ± 8.26 | 75.53 ± 7.78 | 72.17 ± 8.43 | 0.0001 |
| BMI | 27.8 ± 4.7 | 27.9 ± 3.8 | 27.84 ± 4.43 | 0.989 |
| Tobacco: | ||||
| Smoker | 35 (24.1%) | 16 (21.9%) | 51 (23.4%) | 0.715 |
| Former smoker | 110 (75.9%) | 57 (78.1%) | 167 (76.6%) | |
| Packs-year | 47.22 ± 29.27 | 49.58 ± 29.56 | 48.01 ± 29.32 | 0.577 |
| Having cough and expectoration | 72 (49.7%) | 34 (46.6%) | 48.6% | 0.668 |
| Breathlessness scale: mMRC | 1.2 ± 1.05 | 0.78 ± 0.76 | 1.05 ± 0.97 | 0.022 |
| CAT | 10.73 ± 6.89 | 8.59 ± 5.45 | 10.01 ± 6.5 | 0.021 |
| BODEX | 2.02 ± 1.85 | 0.96 ± 1.18 | 1.67 ± 1.73 | 0.0001 |
| CHARLSON INDEXa | 3.07 ± 2.81 | 2.86 ± 2.21 | 3 ± 2.12 | 0.669 |
| Phenotype: | ||||
| Non-exacerbator | 96 (66.2%) | 55 (75.3%) | 151 (69.3%) | 0.168 |
| ACO | 23 (15.9%) | 10 (13.7%) | 33 (15.1%) | 0.674 |
| Emphysematous exacerbator | 8 (5.5%) | 0 | 8 (3.7%) | 0.041 |
| Bronchitis exacerbator | 18 (12.4%) | 8 (11%) | 26 (11.9%) | 0.754 |
| COPD Treatment: | ||||
| LABA | 4 (2.8%) | 4 (5.5%) | 8 (3.7%) | 0.313 |
| LAMA | 18 (12.4%) | 13 (17.8%) | 31 (14.2%) | 0.282 |
| CI | 1 (0.7%) | 0 | 1 (0.5%) | 0.477 |
| LAMA+ LABA | 19 (13.1%) | 7 (9.6%) | 26 (11.9%) | 0.450 |
| LABA +IC | 12 (8.3%) | 6 (8.2%) | 18 (8.3%) | 0.989 |
| LAMA+IC | 4 (2.8%) | 1 (1.4%) | 5 (2.3%) | 0.518 |
| LAMA+ LABA+ IC | 48 (33.1%) | 10 (13.7%) | 58 (26.6%) | 0.002 |
| OTHERS | 4 (2.8%) | 3 (4.1%) | 7 (3.2%) | 0.593 |
| NO TREATMENT | 35 (24.1%) | 29 (39.7%) | 64 (29.4%) | 0.017 |
| Hemoglobin | 14.38 ± 1.6 | 14.60 ± 1.70 | 14.45 ± 1.63 | 0.356 |
| Hematocrit | 43.70± 4.37 | 44.24 ± 4.82 | 43.87 ± 4.51 | 0.407 |
| Leukocytes | 8.23 ± 2.45 | 7.65 ± 1.77 | 8.03 ± 2.26 | 0.071 |
| Eosinophils % | 2.7 ± 1.9 | 3.08 ± 2.5 | 2.82 ± 2.12 | 0.208 |
| Absolute number of eosinophils | 212.07 ± 145.46 | 232.83 ± 206.12 | 219.03 ± 168.03 | 0.391 |
| Correct spirometry % | 97.9% | 100% | 0.216 | |
| Exacerbations** | Media (DS)/mediana IQR | |||
| Outpatient | 3.56 (5.82)/1 (0–4) | 3.10 (4.99)/1 (0–4) | 3.41 (5.56)/1 (0–4) | 0.8* |
| Hospital attention | 1.57 (3.51)/0 (0–2) | 0.77 (2.29)/0 (0–0) | 1.31 (3.18)/0 (0–1) | <0.002* |
Notes: *Mann–Whitney U. **Non-parametric analysis. aAdjusted by age. ¥Value of comparisons by Chi-square/Fisher test or t-test.