Table 2.
Spirometry Differences Between Concordant and Discordant Patients
| Studied Concordant (n=142) | Studied Discordant (n=73) | Total (n=215) | p* | |
|---|---|---|---|---|
| Initial | ||||
| FEV1 mL | 2158 (684) | 2425 (530) | 2249 (647) | 0.004 |
| FEV1% | 70.1 (18.7) | 83. 1 (14.6) | 75 (18.3) | 0.01 |
| FVC mL | 3.632 (982) | 3588 (744) | 3617 (907) | 0.7 |
| FVC % | 87.5 (19.4) | 88.5 (15.9) | 87.9 (18.2) | 0.7 |
| FEV1/FVC | 58.6 (8) | 67.3 (1.9) | 61.6 (7.8) | <0.0001 |
| Final follow-up | ||||
| FEV1 mL | 1841 (626) | 2.067(492) | 1918 (593) | <0.0001 |
| FEV1% | 61 (17.5) | 71.9 (12.3) | 64.7 (17) | <0.0001 |
| FVC mL | 3436 (922) | 3500 (742) | 3547 (865) | 0.7 |
| FVC % | 82.7 (18.5) | 88 (15.9) | 84.5 (17.8) | 0.04 |
| FEV1/FVC | 53.2 (9.2) | 59.2 (6.8) | 55.2 (6.8) | <0.0001 |
| Differences | ||||
| FEV1 mL | −317.3 (356.4) | −357.8 (299.1) | −331 (338) | 0.4 |
| FEV1% | −9.7 (11.6) | −11.2 (10.5) | −10.2 (11.2) | 0.3 |
| FVC mL | −196.1 (645) | −88 (466) | −159.6 (592) | 0.2 |
| FVC % | −4.8 (16.3) | −0.6 (13.5) | −3.4 (15.5) | 0.055 |
| FEV1/FVC | −5.4 (7.6) | −8.1 (6.2) | −6.3 (7.2) | 0.009 |
| Annualized differences | ||||
| FEV1 mL | −31.5 (37.6) | −35.9 (30.8) | −33(35.4) | 0.4 |
| FEV1% | −1 (2.2) | −1.1 (1.1) | −1 (1.2) | 0.4 |
| FVC mL | −18.6 (64.2) | −8.3 (46) | −15 (58.8) | 0.2 |
| FVC % | −0.47 (1.7) | −0.03 (1.4) | −0.32 (1.6) | 0.052 |
| FEV1/FVC | −0.54 (0.8) | 0.82 (0.7) | 0.63 (0.7) | 0.008 |
Notes: *p value by t-test for independent samples. Values expressed as mean (standard deviation).