Table 3.
Univariate Cox Regression Analysis
| Characteristics | Number of Patients | ||
|---|---|---|---|
| 11,620 | Hazard Ratio (95% Confidence Interval) | P | |
| Endometrioma | |||
| No | 7212 | 1 (Reference) | |
| Yes | 4408 | 1.714 (0.838–3.507) | 0.1403 |
| Age | |||
| ≤39 | 5367 | 1 (Reference) | |
| >39 | 6253 | 0.716 (0.348–1.475) | 0.3654 |
| Total /subtotal hysterectomy | |||
| No | 7291 | 1 (Reference) | |
| Yes | 4329 | 0.252 (0.088–0.722) | 0.0103* |
| Ovarian surgery | 0.2753 | ||
| BSO/BO | 3045 | 1 (Reference) | |
| UO/USO ± partial oophorectomy | 979 | 3.047 (0.546–16.988) | 0.2038 |
| Partial oophorectomy | 7596 | 2.253 (0.782–6.494) | 0.1327 |
| Tubal ligation | |||
| No | 11,478 | 1 (Reference) | |
| Yes | 142 | 0 | 0.9847 |
| Pelvic inflammatory disease | |||
| No | 2711 | 1 (Reference) | |
| Yes | 8909 | 0.942 (0.404–2.195) | 0.8892 |
| Infertility | |||
| No | 10,452 | 1 (Reference) | |
| Yes | 1168 | 1.805 (0.691–4.715) | 0.2282 |
| Cardiovascular disease | |||
| No | 10,452 | 1 (Reference) | |
| Yes | 1168 | 0.584 (0.139–2.452) | 0.4626 |
| Diabetes mellitus | |||
| No | 10,255 | 1 (Reference) | |
| Yes | 1365 | 1.086 (0.379–3.112) | 0.8781 |
| Chronic liver disease | |||
| No | 11,259 | 1 (Reference) | |
| Yes | 361 | 0 | 0.9843 |
| Rheumatic disease | |||
| No | 11,089 | 1 (Reference) | |
| Yes | 531 | 1.423 (0.339–5.972) | 0.6302 |
| Charlson comorbidity index | 0.0017** | ||
| 0 | 5749 | 1 (Reference) | |
| 1 | 2391 | 0 | 0.9880 |
| 2 | 1488 | 37.531(4.804–293.193) | 0.0005*** |
| ≥3 | 1992 | 53.484 (7.160–399.531) | 0.0001*** |
Notes: *P < 0.05, **P < 0.01, ***P < 0.001.
Abbreviations: BSO/BO, bilateral salpingo-oophorectomy/bilateral oophorectomy; USO/UO, unilateral salpingo-oophorectomy/unilateral oophorectomy.