. Author manuscript; available in PMC: 2020 Jun 22.

Published in final edited form as: J Toxicol Environ Health A. 2019 Sep 29;82(17):944–955. doi: 10.1080/15287394.2019.1671278

Table 2.

Hemodynamic measures of isolated mouse hearts at baseline before ischemia and reperfusion.

Time Points	Parameters	Filtered Air (n=8)	Fresh DE (n=8)	Aged DE (n=8)
Baseline	HR (bpm)	323±20	304±28	315±30
	LVDP (cmH₂O)	157.7±21.3	79.7±10.7^*	102.5±11.2^*
	dP/dt_max (cmH₂O/sec)	5421±868	3127±561^*	3725±295^*
	dP/dt_min (cmH₂O/sec)	−4023±588	−2300±353^*	−3367±369
	Flow Rate (mL/min)	1.7±0.2	1.6±0.3	2.0±0.2
20 min of reperfusion	HR (bpm)	294±20	286±19	288±16
	LVDP (cmH₂O)	55±16	52±10	45±18
	dP/dt_max (cmH₂O/sec)	2047±624	1798±356	1726±700
	dP/dt_min (cmH₂O/sec)	−1570±424	−1331±271	−1179±533
	Flow Rate (mL/min)	1.8±0.3	1.6±0.2	2.3±0.4
40 min of reperfusion	HR (bpm)	292±20	279±12	279±23
	LVDP (cmH₂O)	63±20	61±12	46±14
	dP/dt_max (cmH₂O/sec)	2375±735	2287±433	1899±628
	dP/dt_min (cmH₂O/sec)	−1814±491	−1554±378	−1432±467
	Flow Rate (mL/min)	1.7±0.3	1.5±0.2	2.3±0.4
60 min of reperfusion	HR (bpm)	285±17	278±14	300±12
	LVDP (cmH₂O)	57±15	63±13	44±9
	dP/dt_max (cmH₂O/sec)	2413±676	2314±426	1829±499
	dP/dt_min (cmH₂O/sec)	−1771±444	−1589±365	−1169±57
	Flow Rate (mL/min)	1.6±0.3	1.4±0.2	1.9±0.4

Values are means ± SE. HR=heart rate, LVDP=left ventricular developed pressure; dP/dt_max=maximum 1^st derivative of the change in left ventricular pressure/time; dP/dt_min=minimum 1^st derivative of the change in left ventricular pressure/time; Flow rate, coronary flow rate.

p < 0.05 compared with FA group at same time point.