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. 2020 Jun 18;13:5795–5805. doi: 10.2147/OTT.S257512

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© 2020 Yang et al.

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B7-H6 regulated the phosphorylation of Ras/MEK/ERK pathway. (A) The effects of B7-H6 on the expression of t-MEK1/2, p-MEK1/2, t-ERK1/2 and p-ERK1/2 were analyzed by Western blot compared with shCtrl and wild-type (WT) groups of Jurkat and Raji cells. (B) The effects of AZD8330 on the expression of B7-H6, t-MEK1/2, p-MEK1/2, t-ERK1/2 and p-ERK1/2 in Jurkat and Raji cells transfected with B7-H6 overexpression (hB7-H6) or the corresponding control-vector (hCtrl) plasmids were evaluated by Western blot. *P<0.05, **P<0.01.