Table 4.
Predictors of HIV infection in singleton infants exposed to HIV
| Unadjusted Odds Ratio (95% Confidence Interval) | P | Adjusted Odds Ratio (95% Confidence Interval) | P | |
|---|---|---|---|---|
| No maternal ARV use | 7.9 (2.1–30.2) | 0.002 | 13.5 (2.5–72.1) | 0.002 |
| Preterm delivery | 5.1 (1.4–19.4) | 0.02 | 5.3 (1.1–25.1) | 0.04 |
| Intravenous drug use | 5.2 (1.0–26.0) | 0.04 | 4.3 (0.7–28.7) | 0.1 |
| Prenatal care | 0.2 (0.03–0.9) | 0.04 | 2.5 (0.3–20)* | 0.4 |
| Cesarean delivery | 2.8 (0.6–13.5) | 0.2 | ||
| HIV RNA viral load > 1,000 copies/mL | 2.6 (0.4–15.9) | 0.3 | ||
| Timing of maternal HIV diagnosis | 1.4 (0.3–6.7) | 0.7 |
Adjusted model, n= 560.
Prenatal care became a positive association in multivariate analysis. We believe this occurred because there were so few women in this category; there were zero women with an HIV infected infant who were not taking ARVs and did not receive PNC, but there were 2 women taking ARVs who did not receive prenatal care that had HIV-infected infant.