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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Brain Stimul. 2020 Apr 1;13(4):1014–1023. doi: 10.1016/j.brs.2020.03.016

Figure 5. Histology and colocalization map for acutely treated or sham treated AD mice.

Figure 5.

Representative treated (left column) and corresponding sham treated (right column) histology (top of each figure) and map of colocalized activated microglia and plaque (bottom of each figure). The color scheme refers to the percentage of activated microglia colocalized with plaque. Note the following correspondence between image pairs here and the quantitative analysis results in Table 1. (A) This image corresponds to treated mouse #1 while (B) corresponds to sham treated mouse #1. (C) This image corresponds to treated mouse #5 while (D) corresponds to sham treated mouse #5. Overall, we observed a statistically significant difference between colocalization maps of actual and sham treated mice, e.g., between treated side and the entire sham brain (36.0 +/− 4.6% versus 14.2 +/− 2.6%, z = 0.245, p < 0.014).