Table 2.
Intraoperative Outcomes
| Variables | Stentless Valve Replacement | Age | p-value* | |||
|---|---|---|---|---|---|---|
| <40 | 40–59 | 60–74 | ≥75 | |||
| (n=1947) | (n=105) | (n=528) | (n=860) | (n=454) | ||
| Primary Indication for Operation | <0.001 | |||||
| Aortic Insufficiency | 393 (20) | 41 (39) | 140 (27) | 157 (18) | 55 (12) | |
| Aortic Stenosis | 1168 (60) | 38 (36) | 260 (49) | 522 (61) | 348 (77) | |
| Aortic Root Aneurysm | 227 (12) | 10 (9.5) | 83 (16) | 107 (12) | 27 (5.9) | |
| Aortic Dissection | 101 (5) | 9 (8.6) | 35 (6.6) | 45 (5.2) | 12 (2.6) | |
| Unknown | 58 (3) | 7 (6.7) | 10 (1.9) | 29 (3.4) | 12 (2.6) | |
| Concomitant Procedures | ||||||
| CABG | 429 (22) | 1 (1) | 69 (13) | 236 (27) | 123 (27) | <0.001 |
| Mitral Valve Surgery | 186 (9.6) | 5 (4.8) | 45 (8.5) | 76 (8.8) | 60 (13) | 0.012 |
| Tricuspid Valve Surgery | 70 (3.6) | 1 (1.0) | 17 (3.2) | 36 (4.2) | 16 (3.5) | 0.361 |
| Ascending Aorta or Arch Replacement | 769 (40) | 51 (49) | 254 (48) | 352 (41) | 112 (25) | <0.001 |
| CPB Time (minutes) | 181 (149, 223) | 170 (149, 210) | 180 (153, 220) | 184 (150, 229) | 177 (143, 214) | 0.015 |
| Clamp Time (minutes) | 144 (117, 179) | 138 (115, 171) | 146 (121, 179) | 147 (119, 183) | 139 (112, 173) | 0.005 |
| Blood Transfusion, PRBC (units) | 2 (1, 4) | 2 (0,3) | 2 (0,4) | 2 (1,5) | 4 (2,5) | <.0001 |
| 0 | 691 | 55(52.4) | 257 (48.7) | 294 (34.2) | 85 (18.7) | <.0001 |
| 1–2 units | 460 | 25 (23.8) | 123 (23.3) | 213 (24.8) | 99 (21.8) | |
| 3–4 units | 404 | 14 (13.3) | 73 (13.8) | 167 (19.4) | 150 (33.0) | |
| > 4 units | 392 | 11 (10.5) | 75 (14.2) | 186 (21.6) | 120 (26.4) | |
| Implant Size (mm) | 26 (25, 27) | 27 (25, 29) | 27 (25, 29) | 25 (25, 27) | 25 (23, 27) | <0.001 |
| Technique of Freestyle | 0.441 | |||||
| Modified Inclusion | 1812 (93) | 98 (93) | 494 (94) | 792 (92) | 428 (94) | |
| Total Root | 60 (3.1) | 3 (2.9) | 21 (4.0) | 28 (3.3) | 8 (1.8) | |
| Subcoronary | 12 (0.6) | 1 (1.0) | 2 (0.4) | 7 (0.8) | 2 (0.4) | |
| Unknown | 63 (3.2) | 3 (2.9) | 11 (2.1) | 33 (3.8) | 16 (3.5) | |
Data presented as median (25 %, 75 %) for continuous data and n (%) for categorical data. P-value < 0.05 defined as statistically significant difference between the four age groups. Abbreviations: CABG, coronary artery bypass graft; CPB, cardiopulmonary bypass; PRBC, packed red blood cells.
*:
After Bonferroni correction, p<0.0045 was considered significant.