Figure 4.

Examples of proteins with multiple PTMs, showing the pathway of the protein, the sequence with sulfate groups (SO₄) attached to Tyr (Y) residues, and reported O-glycosylation sites (yellow square- GalNAc residues) in the peptide sequences. Phosphate groups (PO₃) are also indicated In OPN the integrin binding domain RGD is underlined, for US28 the two O-glycosylation sites were not unambiguously identified and can be located on any of the 5 Thr marked. The amino acids in the sequence are noted, along with a diagram of where the sequence is located in the protein. The protein function of the shown domain or sequence is noted in the right column. Abbreviations: CCR5: CC chemokine receptor 5, S1PR1 :Sphingosine-1-phosphate receptor 1, FRP-1 : Secreted frizzled-related protein 1, PSGL-1: P-selectin glycoprotein ligand 1, US28: G-protein coupled receptor homolog US28.