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. 2020 Jun 22;10:10087. doi: 10.1038/s41598-020-66921-x

Table 2.

Biochemical indexes for predicting SAP in the patients with APIP.

Variables AUC 95%CI P Value Cut-off Sensitivity Specificity +LR -LR
WCC(×10^9/L) 0.713 0.607 to 0.818 0.001 12.99 0.765 0.576 1.80 0.41
Neu(×10^9/L) 0.707 0.602 to 0.813 0.001 11.64 0.794 0.561 1.81 0.37
Glucose(mmol/L) 0.666 0.543 to 0.788 0.007 6.62 0.706 0.636 1.94 0.46
Albumin(g/L) 0.659 0.547 to 0.771 0.009 35.65 0.515 0.824 2.93 0.59
RDW(%) 0.656 0.547 to 0.764 0.011 14.35 0.882 0.439 1.57 0.27
NLR 0.659 0.550 to 0.769 0.009 12.79 0.824 0.470 1.55 0.37
LMR 0.715 0.605 to 0.824 <0.001 1.51 0.727 0.735 2.74 0.37
PNI 0.657 0.543 to 0.771 0.010 38.60 0.652 0.735 2.46 0.47
BUN(mmol/L) 0.659 0.538 to 0.779 0.011 4.10 0.455 0.877 3.70 0.62
Scr(umol/L) 0.688 0.567 to 0.809 0.002 48.70 0.758 0.600 1.90 0.40
ALT(IU/L) 0.630 0.517 to 0.744 0.036 25.00 0.818 0.415 1.40 0.44
ALT/AST 0.698 0.576 to 0.744 0.001 0.61 0.636 0.800 3.18 0.46
LDH(IU/L) 0.777 0.676 to 0.877 <0.001 263.00 0.594 0.879 4.91 0.46
Calcium(mmol/L) 0.668 0.549 to 0.787 0.009 2.075 64.5 65.6 1.38 0.28
TG(mmol/L) 0.661 0.543 to 0.779 0.012 5.16 0.781 0.552 1.74 0.40
TC(mmol/L) 0.649 0.525 to 0.772 0.020 7.03 0.750 0.569 1.74 0.44

−LR, negative likelihood ratio; +LR, positive likelihood ratio; AUC, area under the receiver operating characteristic curve; PNI, prognostic nutritional index, were calculated as albumin (g/L) plus 5 × total lymphocyte count (10^9/L).