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. 2020 Jan 20;27(7):2131–2142. doi: 10.1038/s41418-020-0490-7

Fig. 6. PHD(H196A) knock-in had little effect on DSS-induced colitis.

Fig. 6

a–f Age-matched (8–10 weeks old) male littermates (the body weight of the mice is within normal limits) were treated with DSS (2.5% in drinking water) for 7 days. After treatment, the mice were sacrificed. Each group had five mice. a Mice body weight. Data are mean ± SEM. The P value was calculated using two-way ANOVA. b Representative of mice colons. c The colon length of mice. Data are mean ± SEM. The P value was calculated using two-way ANOVA. d Disease activity index of mice. Data are mean ± SEM. Statistical analysis was performed using two-way ANOVA. e H&E staining of colon tissue sections of mice. f Determination of mRNA levels of Tnfα, Il-1β, and Il-6 in mice colon mucosa (n = 5). The data are mean ± SEM. Scale bar = 100 µm. **P < 0.01; ***P < 0.001. ns no significance.