Table 1.
Comparison between the Non-round and Round Groups in Myopic Congenital Glaucoma.
Parameter | Non-round group | Round group | P value* |
---|---|---|---|
Number of eyes | 28 | 23 | |
Ovality index |
1.489 ± 0.224 (1.111–1.944) |
1.042 ± 0.024 (1.011–1.085) |
0.036 |
Demographics | |||
Sex (female/male) | 15/13 | 7/16 | 0.206 |
First surgery age (months) |
2.8 ± 2.4 (0.16–7.57) |
15.2 ± 8.9 (3.87–34.07) |
<0.001 |
First surgery age for the eyes with recent axial length between 25.0 and 29.0 mm (months) |
2.5 ± 2.1 (0.16–7.54) |
15.1 ± 8.5 (3.87–34.07) |
0.018 |
Preoperative findings | |||
IOP (mmHg) | 31.4 ± 7.1 | 28.7 ± 4.2 | 0.134 |
Follow-up biometrics | |||
Recent axial length (mm) | 29.5 ± 2.5 | 27.1 ± 1.4 | 0.004 |
High myopia (>26.0 mm), % | 96.4 | 82.6 | 0.132 |
Axial length around 10 years (mm) | 28.9 ± 2.5 | 26.9 ± 1.4 | 0.030 |
PPS-ONH OCT parameters | |||
BM without RPE (zone β) | 266.0 ± 215.2 | 28.8 ± 51.2 | 0.002 |
Scleral border tissue length (zone γ) (µm) | 828.4 ± 824.1 | 22.2 ± 48.8 | <0.001 |
Horizontal BMO diameter (µm) | 2258.0 ± 943.3 | 1631.4 ± 264.7 | 0.013 |
Vertical BMO diameter (µm) | 2176.4 ± 505.9 | 1661.3 ± 246.8 | 0.006 |
Average BMO diameter (µm) | 2187.2 ± 604.7 | 1641.6 ± 205.3 | 0.003 |
Ratio of H/V BMO diameter | 0.985 ± 0.194 | 0.982 ± 0.061 | 0.933 |
Macular BM distance (µm) | 3906.4 ± 791.6 | 3860.0 ± 313.0 | 0.811 |
Mean LC depth (µm) | 565.9 ± 225.7 | 602.6 ± 194.6 | 0.539 |
Macular BM curvature angle (°) | 2.78 ± 0.2.60 | −0.41 ± 0.92 | 0.039 |
Subfoveal choroidal thickness (µm) | 184.9 ± 107.7 | 322.9 ± 89.6 | 0.002 |
Follow-up clinical parameters | |||
IOP at OCT measurements (mmHg) | 14.9 ± 3.38 | 16.0 ± 3.92 | 0.437 |
Follow-up period (years) | 12.2 ± 4.2 | 14.6 ± 5.4 | 0.128 |
Total number of surgeries (times) | 2.81 ± 1.76 | 2.13 ± 0.99 | 0.124 |
Age at the last surgery (years) |
3.44 ± 4.67 (0.01–19.06) |
4.98 ± 4.70 (0.45–15.70) |
0.394 |
Final BCVA (LogMAR)† | 0.798 ± 0.797 | 0.633 ± 0.637 | 0.479 |
Values are mean ± standard deviation (range) unless otherwise specified.
IOP = intraocular pressure, PPS = peripapillary sclera, ONH = optic nerve head, OCT = optical coherence tomography, BM = Bruch’s membrane, RPE = retinal pigment epithelium, BMO = Bruch’s membrane opening, H/V = horizontal/vertical, LC = lamina cribrosa, BCVA = best corrected visual acuity, LogMAR = logarithm of the Minimum Angle of Resolution.
*P value was calculated using generalised estimating equation analysis.
†The arbitrary LogMAR values for visual acuity less than counting fingers were used as follows: counting fingers were converted to 2.0 LogMAR units, hand motions were converted to 2.3 LogMAR units, light perception was converted to 2.5 LogMAR units, and no light perception was converted to 3.0 LogMAR units68.