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. 2020 Jun 22;10:10041. doi: 10.1038/s41598-020-67051-0

Table 1.

Comparison between the Non-round and Round Groups in Myopic Congenital Glaucoma.

Parameter Non-round group Round group P value*
Number of eyes 28 23
Ovality index

1.489 ± 0.224

(1.111–1.944)

1.042 ± 0.024

(1.011–1.085)

0.036
Demographics
  Sex (female/male) 15/13 7/16 0.206
  First surgery age (months)

2.8 ± 2.4

(0.16–7.57)

15.2 ± 8.9

(3.87–34.07)

<0.001
  First surgery age for the eyes with recent axial length between 25.0 and 29.0 mm (months)

2.5 ± 2.1

(0.16–7.54)

15.1 ± 8.5

(3.87–34.07)

0.018
Preoperative findings
  IOP (mmHg) 31.4 ± 7.1 28.7 ± 4.2 0.134
Follow-up biometrics
  Recent axial length (mm) 29.5 ± 2.5 27.1 ± 1.4 0.004
  High myopia (>26.0 mm), % 96.4 82.6 0.132
  Axial length around 10 years (mm) 28.9 ± 2.5 26.9 ± 1.4 0.030
PPS-ONH OCT parameters
  BM without RPE (zone β) 266.0 ± 215.2 28.8 ± 51.2 0.002
  Scleral border tissue length (zone γ) (µm) 828.4 ± 824.1 22.2 ± 48.8 <0.001
  Horizontal BMO diameter (µm) 2258.0 ± 943.3 1631.4 ± 264.7 0.013
  Vertical BMO diameter (µm) 2176.4 ± 505.9 1661.3 ± 246.8 0.006
  Average BMO diameter (µm) 2187.2 ± 604.7 1641.6 ± 205.3 0.003
  Ratio of H/V BMO diameter 0.985 ± 0.194 0.982 ± 0.061 0.933
  Macular BM distance (µm) 3906.4 ± 791.6 3860.0 ± 313.0 0.811
  Mean LC depth (µm) 565.9 ± 225.7 602.6 ± 194.6 0.539
  Macular BM curvature angle (°) 2.78 ± 0.2.60 −0.41 ± 0.92 0.039
  Subfoveal choroidal thickness (µm) 184.9 ± 107.7 322.9 ± 89.6 0.002
Follow-up clinical parameters
  IOP at OCT measurements (mmHg) 14.9 ± 3.38 16.0 ± 3.92 0.437
  Follow-up period (years) 12.2 ± 4.2 14.6 ± 5.4 0.128
  Total number of surgeries (times) 2.81 ± 1.76 2.13 ± 0.99 0.124
  Age at the last surgery (years)

3.44 ± 4.67

(0.01–19.06)

4.98 ± 4.70

(0.45–15.70)

0.394
  Final BCVA (LogMAR) 0.798 ± 0.797 0.633 ± 0.637 0.479

Values are mean ± standard deviation (range) unless otherwise specified.

IOP = intraocular pressure, PPS = peripapillary sclera, ONH = optic nerve head, OCT = optical coherence tomography, BM = Bruch’s membrane, RPE = retinal pigment epithelium, BMO = Bruch’s membrane opening, H/V = horizontal/vertical, LC = lamina cribrosa, BCVA = best corrected visual acuity, LogMAR = logarithm of the Minimum Angle of Resolution.

*P value was calculated using generalised estimating equation analysis.

The arbitrary LogMAR values for visual acuity less than counting fingers were used as follows: counting fingers were converted to 2.0 LogMAR units, hand motions were converted to 2.3 LogMAR units, light perception was converted to 2.5 LogMAR units, and no light perception was converted to 3.0 LogMAR units68.