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. 2020 Jan 28;27(7):2206–2216. doi: 10.1038/s41418-020-0496-1

Fig. 3. BAFF leads to NF-κB-dependent mTORC1 activation.

Fig. 3

a CLL cells were pretreated with 5 μM BMS-345541 for 1 hr followed by 3 hr BAFF treatment. Phosphorylated and total ribosomal S6 protein were examined by IB. Hsp90 was used as loading control. b Relative phosphorylated S6 amounts of CLL cells treated as in (a). Mean ± sem. n = 3. *p < 0.05. c CLL cells were pretreated with rapamycin for 1 hr and then stimulated with BAFF as indicated. Presence of p62, non-phosphorylated and phosphorylated ribosomal S6 protein were analyzed by IB.