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. 2020 Jun 16;8:631. doi: 10.3389/fbioe.2020.00631

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Copyright © 2020 Patel, Thakur, Kushwah, Patil, Nile, Jain, Banerjee and Kai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Uptake of (A) free C-6 and (B) C6-LNP by MCF-7 cells (a) green fluorescence of C-6. (b) Corresponding DIC images (c) overlay of (a,b), and (d,e) vertical and horizontal line series analysis long the white line of image (c). (C) Cell cytotoxicity of QC, MPA, combination of MPA + QC, QC-LNP, MPA-LNP and combination of MPA-LNP + QC-LNP after 24 h. Each data point represented as mean ± SD (n = 4). (D) Effect of MPA and MPA-LNP on inosine-5′-monophosphate dehydrogenase activity in MCF-7 cell lines.